micro-community-banner
 
  • Saved
Investigating the association of atopic dermatitis with ischemic stroke and coronary heart disease: A mendelian randomization study

Investigating the association of atopic dermatitis with ischemic stroke and coronary heart disease: A mendelian randomization study

Source : https://www.frontiersin.org/articles/10.3389/fgene.2022.956850/full

Background: Atopic dermatitis (AD) is the most common chronic skin inflammatory disease. Prior observational studies have reported inconsistent results on the association of AD with ischemic stroke and coronary heart...


Conclusion: Our MR study does not support a causal association of genetically predicted AD with ischemic stroke, large artery stroke, cardioembolic stroke, small vessel stroke, coronary heart disease, and myocardial infarction.

  • Saved
Association of atopic diseases with atrial fibrillation risk: A systematic review and meta-analysis

Association of atopic diseases with atrial fibrillation risk: A systematic review and meta-analysis

Source : https://www.frontiersin.org/articles/10.3389/fcvm.2022.877638/full

BackgroundAtopic diseases and atrial fibrillation (AF) seem to share an underlying inflammatory pathology. To date, some population-based studies have explored the relationship between the two. We aimed to conduct a...


Conclusion: This meta-analysis demonstrated that patients with atopic diseases have a higher risk of developing AF, particularly those with asthma.

  • Saved
A Review of Phase 3 Trials of Dupilumab for the Treatment of Atopic Dermatitis in Adults, Adolescents, and Children Aged 6 and Up - Dermatology and Therapy

A Review of Phase 3 Trials of Dupilumab for the Treatment of Atopic Dermatitis in Adults, Adolescents, and Children Aged 6 and Up - Dermatology and Therapy

Source : https://link.springer.com/article/10.1007/s13555-022-00778-y

Atopic dermatitis (AD) is a chronic pruritic skin disease that can have a profound negative impact on patients' quality of life, especially in cases of inadequate disease control. Dupilumab, a...


Conclusion: In summary, phase 3 clinical trials of dupilumab demonstrate that dupilumab provides a multidimensional benefit in patients ages 6 years and older with moderate-to-severe AD, with rapid and sustained improvements in AD signs and symptoms and an acceptable safety profile.

  • 3yr
    This article helps to solidify that dupixent is an excellent first line medicine for moderate to severe AD. It is a go-to medicine in my practice. My experience Show More
  • 3yr
    Indeed, we should feel very comfortable prescribing dupixent - minimal side effects and no lab monitoring needed - and now also approved for children aged 6 months to 5 years Show More
  • Saved
Atopic dermatitis and risk of major neuropsychiatric disorders in children: a population-based cohort study - PubMed

Atopic dermatitis and risk of major neuropsychiatric disorders in children: a population-based cohort study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36018560/

The was no substantial impact of AD on the overall risk of many neuropsychiatric conditions in children, but disease severity and age may be important modifying factors. Additional research is...


Conclusion: There was no substantial impact of AD on the overall risk of many neuropsychiatric conditions in children, but disease severity and age may be important modifying factors.

  • Saved
Taking Vitamin D Supplements While Pregnant Can Reduce Your Child's Risk of Eczema

Taking Vitamin D Supplements While Pregnant Can Reduce Your Child's Risk of Eczema

Source : https://scitechdaily.com/taking-vitamin-d-supplements-while-pregnant-can-reduce-your-childs-risk-of-eczema/

Prenatal vitamin D supplementation may reduce the risk of eczema in newborns. According to a recent study by doctors at the University of Southampton, using vitamin D supplements during pregnancy...


Discussion: The study, which was published in the British Journal of Dermatology, found that women who took 1000 international units (IU) of vitamin D daily from 14 weeks of pregnancy until delivery had a decreased chance of their babies developing atopic eczema in the first year.