Atopic Dermatitis: Sailing beyond the Sunset with a Multitude of Novel Treatments
Source : https://www.mdpi.com/2077-0383/11/12/3475/htm
Atopic eczema or dermatitis (AD) is a chronic pruritic inflammatory cutaneous disorder with an incidence up to 20% in children and 10% in adults depending on region and ethnicity. Due...
Conclusion: Even as the present has revolutionized our view and treatment of AD, the future holds even more hope for the patients; multiple clinical trials and subpopulations analysis are currently.
Review of Ruxolitinib in the Treatment of Atopic Dermatitis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35674400/
1 Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC, USA. 2 Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC, USA. 3 Department...
Conclusion: Data from phase II and III clinical trials in adult patients suggest RUX is an effective and safe therapy for AD.
Sodium Intake Linked to Risk for Atopic Dermatitis
Source : https://www.physiciansweekly.com/sodium-intake-linked-to-risk-for-atopic-dermatitis/
TUESDAY, May 31, 2022 (HealthDay News) -- Increased consumption of dietary sodium may increase the risk for atopic dermatitis, according to a study presented at the annual meeting of the...
"These data support salt restriction as a low-cost, safe intervention for atopic dermatitis that could be offered in diverse settings, although additional research is needed using more specific measures of atopic dermatitis in a longitudinal population cohort," the authors write.
New Insight into Drugs to Alleviate Atopic March via Network Pharmacology-Based Analysis
Source : https://doi.org/10.3390/cimb44050153
In the present study, a subject of atopic dermatitis (AD) is exposed progressively to allergic rhinitis (AR) and asthma (AS), which is defined as atopic march (AM). However, both the...
The network analysis unveiled key targets against AM, and the MDT confirmed the affinity between significant compounds and targets. In this study, we described the significance of the eight uppermost targets (CCL2, CTLA4, CXCL8, ICAM1, IL10, IL17A, IL1B, and IL2) and eight ligands (Bindarit, CTLA-4 inhibitor, Danirixin, A-205804, AX-24 HCl,...
Longitudinal course and predictors of depressive symptoms in atopic dermatitis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35551964/
1 Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC USA. 2 Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL USA....
Conclusion: Depressive symptoms are closely related to and fluctuate with AD severity over time. Improved control of AD signs and symptoms, particularly itch, may secondarily improve mental health.