Increasing severity of early-onset atopic dermatitis, but not late-onset, associates with development of aeroallergen sensitization and allergic rhinitis in childhood - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34558075/
1 COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. 2 Department of Pediatrics, Slagelse Sygehus, Slagelse, Denmark. Background: Early exposure to...
Conclusion: Increasing severity of early-onset AD, but not late-onset AD, associates with aeroallergen sensitization and allergic rhinitis later in childhood.
Obstructive sleep apnea in patients with severe asthma: Prevalence and association between severity and asthma control Al-Lawati F, Al-Mubaihsi SM, Jayakrishnan B, Rizvi S, Al-Abri MA - Ann Thorac Med
ORIGINAL ARTICLE Year : 2022 | Volume : 17 | Issue : 2 | Page : 118-123 Obstructive sleep apnea in patients with severe asthma: Prevalence and association between severity...
Conclusions: The prevalence of OSA was high (32.37%) in patients with severe asthma. Uncontrolled severe asthma was significantly associated with severe OSA.
A Maximum-Use Trial of Ruxolitinib Cream in Adolescents and Adults with Atopic Dermatitis - American Journal of Clinical Dermatology
Source : https://link.springer.com/article/10.1007/s40257-022-00690-3
Background Ruxolitinib cream is a topical formulation of ruxolitinib, an inhibitor of Janus kinase 1 and Janus kinase 2. Objective We aimed to determine the safety, tolerability, and bioavailability of...
Conclusions: Under maximum-use conditions, ruxolitinib cream was generally well tolerated, with approximately one-third of patients experiencing treatment-emergent adverse events and few treatment-related adverse events. The mean steady-state plasma concentration of ruxolitinib was well below the level expected to affect bone marrow production...
Conclusion: People with AD have an increased risk of multiple autoimmune conditions, especially those with more severe AD.
Highlights:
• Tetrahydrocurcumin entrapped hybrid colloid as food additive was assembled and investigated.
• The oral administration of TCCHC can alleviate the symptoms of atopic dermatitis in NC/Nga animal model.
• TCCHC might be a promising new functional food additive for AD patients.