Efficacy and Treatment Satisfaction of Different Systemic Therapies in Children and Adolescents with Moderate-to-Severe Atopic Dermatitis: A Real-World Study
Source : https://www.mdpi.com/2077-0383/12/3/1175
For the treatment of moderate-to-severe atopic dermatitis in children and adolescents, the monoclonal antibody dupilumab and the selective JAK-1 inhibitor upadacitinib are two modern systemic therapies approved for long-term treatment....
Conclusions: Our results support the notion that children and adolescents with moderate-to-severe atopic dermatitis benefit from systemic treatment, which can significantly improve
the severity of eczema, the intensity of itching and the quality of life (patients and relatives).
Supplement Individual Article: The Importance of a Healthy Skin Barrier From the Cradle to the Grave Using Ceramide-Containing Cleansers and Moisturizers: A Review and Consensus - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36745380/
Adjunctive daily skin care throughout life promotes a healthy skin barrier and is beneficial in managing various inflammatory skin disorders in all populations. However, when choosing optimal treatment and skin...
Conclusions: International clinical practice guidelines recommend barriersupporting products (including those that contain ceramides) to promote a healthy skin barrier and reduce the symptoms and severity of various inflammatory skin diseases. Gentle cleansers and ceramide-containing moisturizers are beneficial and safe in neonates, young...
Conclusion: Due to physicochemical characterization, the chemical composition of coconut oils investigated in the latest study had diverse composition profiles by fatty acid-containing concentration and percentage. Coconut oil doesn't show any sensitivity and high potential for antibacterial activity due to the high contents of medium and...
Allergic Contact Dermatitis in Refractory Brick Production Worker: A Case Report
In this study, we investigated a 42-year-old man working in a refractory brick (RB) production line who had allergic contact dermatitis (ACD) due to skin exposure to chromium (Cr). He...
Conclusions: Refractory bricks have different compounds that can withstand various temperature ranges. Cr is one of the additives in the production of RB, which can cause ACD in exposed workers. ACD results from a cell-induced immune hypersensitivity reaction (type 4), which is less common in adults than irritant contact dermatitis. Temporary...
An Overview of the Treatment Landscape for Patients With Atopic Dermatitis: Dr Jerry Bagel
A better understanding of the pathogenesis of eczema has brought new biologic agents and oral medications to market, which have proved effective in treating atopic dermatitis (AD), explained Jerry Bagel,...
Conclusions: DiscussionDespite a recent influx of new treatments, it is crucial to remind patients there is no cure for atopic dermatitis and follow-up care is important, explained Jerry Bagel, MD, director of the Eczema Treatment Center of New Jersey.