The increased prevalence of keloids in atopic dermatitis patients with allergic comorbidities: a nationwide retrospective cohort study - Scientific Reports
Source : https://www.nature.com/articles/s41598-021-03164-4
Atopic dermatitis (AD) is associated with allergic comorbidities, such as asthma, allergic rhinitis (AR), and allergic contact dermatitis (ACD). The etiology of keloid is largely unknown; however, AD and keloid...
The prevalence of keloids was higher in the AD group than in the control group. Among patients with AD, adolescents and adults had a higher prevalence of keloids than infants and children. The risk of keloids was high with AD alone, and coexisting asthma significantly increased the risk. Similarly, the risk of keloids was higher in AR...
Significance: Our research further proved that polysaccharide Sacran has anti-dermatitis effects, and also clarified its mechanism of alleviating dermatitis by inhibiting the activation of Th2 cells and reducing the release of IgE, which provides a theoretical basis for the future clinical transformation of polysaccharide Sacran.
Fibrin(ogen) Mechanistically Contributes to Atopic Dermatitis Pathogenesis and Allergic Sensitization | ScienceGate
Source : https://www.sciencegate.app/document/10.1182/blood-2021-153782
Abstract Adults with atopic dermatitis (AD) have an increased risk for thromboembolic events. While coagulation is critical for almost all healing responses, dysregulated clotting and fibrin(ogen) deposition lead to inflammation...
Thus, our findings suggest that fibrin(ogen) plays a critical mechanistic role in driving AD development and allergic sensitization. While fibrinogen's role in established allergic disease has been shown, these novel findings suggest a critical role for fibrinogen in allergic disease pathogenesis which may allow for additional therapeutic...
Atopic dermatitis: disease characteristics and comorbidities in smoking and non-smoking patients from the TREATgermany registry - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34743344/
doi: 10.1111/jdv.17789. Online ahead of print. 1 Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, Munich, Germany. 2 Center of Evidence-Based Healthcare, University Hospital Carl Gustav...
Conclusions: German registry data indicate that AD patients who smoke have a higher disease burden with a different distribution pattern of lesions in adult-onset AD.
The Suppressive Effect of Mamiran Cream on Atopic Dermatitis-Like Skin Lesions In Vivo
Source : https://www.hindawi.com/journals/ecam/2021/2854238/
Background . The Chinese herbal formula Mamiran cream (MMC) has been known for its ameliorative effects on diverse skin diseases, such as eczema. Atopic dermatitis (AD; eczema) is a chronic...
Conclusions: Our findings suggest that MMC exhibits the inhibitory effect on AD, suggesting that MMC may be a potential therapeutic agent for this atopic disorder.