A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34561424/
Atopic dermatitis (AD) is a common chronic pruritic inflammatory skin disorder characterized by recurrent eczematous lesions. Interleukin (IL)-33, a cytokine of the IL-1 family, was found to play an important...
Sweat Droplets Detection Using Image Segmentation on Skin Surface for Evaluation of Sweating Responses to Thermal Stimulus in Atopic Dermatitis
Source : https://ieeexplore.ieee.org/abstract/document/9531894
In this paper, we propose a method for automatically detecting sweat droplets from images taken by replicas of the silicone skin surface created by the Impression Mold Technique (IMT) to...
Skin dysbiosis in the microbiome in atopic dermatitis is site-specific and involves bacteria, fungus and virus - BMC Microbiology
Source : https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-021-02302-2
Background Microbial dysbiosis with increased Staphylococcus aureus (S. aureus) colonization on the skin is a hallmark of atopic dermatitis (AD), however most microbiome studies focus on bacteria in the flexures...
Conclusions
Our data indicate a global and site-specific dysbiosis in AD, involving both bacteria, fungus and virus. When defining targeted treatment clinicians should both consider the individual and skin site and future research into potential crosstalk between microbiota in AD yields high potential.
Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34454985/
These findings elucidate novel genetic pathways involved in AD pathophysiology. The likely involvement of desmocollin 1 and serpin family B member 7 in AD pathogenesis may offer opportunities for the...
Atopic dermatitis is not associated with SARS-CoV-2 outcomes - Archives of Dermatological Research
Source : https://link.springer.com/article/10.1007/s00403-021-02276-1
Atopic dermatitis is characterized by immune dysregulation, which may predispose toward worse COVID-19 outcomes. We conducted a retrospective cohort study to investigate the relationship of atopic dermatitis with COVID-19 symptom...