Atopic Dermatitis Connect
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Janus kinase inhibitors for the therapy of atopic dermatitis

Janus kinase inhibitors for the therapy of atopic dermatitis

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439108/

The JAK-STAT pathway is involved in the signaling of multiple cytokines driving cutaneous inflammation in atopic dermatitis (AD). Janus kinase (JAK) inhibitors target individual receptor-associated kinases, thereby preventing the mediation...

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Atopic dermatitis in adults: a population‐based study in Finland

Atopic dermatitis in adults: a population‐based study in Finland

Source : https://onlinelibrary.wiley.com/doi/full/10.1111/ijd.15912

Ville Kiiski MD , Alexander Salava MD, PhD , Päivikki Susitaival MD, PhD , Satu Barnhill MD, MSc , Anita Remitz MD, PhD , Markku Heliovaara MD, PhD , National...

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Efficacy and safety of topical Janus kinase and phosphodiesterase inhibitor-4 inhibitors for the treatment of atopic dermatitis: A network meta-analysis - PubMed

Efficacy and safety of topical Janus kinase and phosphodiesterase inhibitor-4 inhibitors for the treatment of atopic dermatitis: A network meta-analysis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34487567/

Topical Janus kinase (JAK) and phosphodiesterase-4 (PDE4) inhibitors are novel treatment approaches for atopic dermatitis (AD). This study aimed to compare the efficacy and safety of JAK and PDE4 inhibitors...