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National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis

National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis

Source : https://www.mdpi.com/2077-0383/11/17/5204

Atopic dermatitis (AD) is a common inflammatory skin disease often associated with a significant impairment in the quality of life of affected patients. The Italian Society of Dermatology and Venereology...


Conclusion: This study underlines the utility of organizing information campaigns on AD to enhance awareness regarding disease features and management and to facilitate early diagnosis with a subsequent reduction in the burden of disease.

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Defining mast cell differentiation and heterogeneity through single-cell transcriptomics analysis - PubMed

Defining mast cell differentiation and heterogeneity through single-cell transcriptomics analysis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36205448/

Mast cells (MCs) are widely recognized as central effector cells during type 2 inflammatory reactions and thought to also play a role in innate immune responses, wound healing, and potentially...


Discussion: With the increasing prevalence of newer transcriptomics-based technologies, such as Cellular Indexing of Transcriptomes and Epitopes (CITE-seq), allowing for the simultaneous evaluation of surface protein expression and transcript expressions, allowing for the improved identification of specific markers for each MC phenotype, and...

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Clinical Efficacy of a Digital Intervention for Patients with Atopic Dermatitis: a Prospective Single-Center Study - Dermatology and Therapy

Clinical Efficacy of a Digital Intervention for Patients with Atopic Dermatitis: a Prospective Single-Center Study - Dermatology and Therapy

Source : https://link.springer.com/article/10.1007/s13555-022-00821-y

Introduction Improving disease awareness and treatment adherence is key for the long-term management of atopic dermatitis (AD). Digital interventions can support patients in disease self-management and adopting a healthier lifestyle...


Conclusion: Patients with AD are open to and can benefit from a digitally delivered targeted intervention, as demonstrated by significant improvements in treatment adherence and related clinical outcomes.

  • 3yr
    Yes, it seems that digital interventions are here to stay and generally well-regarded by patients. Personally, I don't recommend them much unless a patient specifically asks about them since there Show More
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Conclusion: Clinicians and patients are encouraged to incorporate these well-validated, quick-to-perform, and easy-to-use instruments into their clinic, selecting the instruments that best fit their need. These assessments are meant to enhance, not replace, the patient–clinician encounter, and to support real-world research and health care...

  • 3yr
    It is truly difficult to objectively measure subjective symptoms such as itch intensity in patients when seen in the office - what bothers one patient tremendously may not burden another Show More
  • 3yr
    Due to its inherent subjectivity, properly and objectively measuring itch intensity in patients has proven to be a difficult challenge. Nonetheless, trying to do this as accurately as possible Show More

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Cognitive-behavioral intervention for anxiety associated with food allergy in a clinical sample of children

Source : https://www.annallergy.org/article/S1081-1206(22)01769-0/fulltext

Although some measure of caution is healthy and adaptive for those with food allergy (FA) to reduce risk of accidental ingestion, clinically impairing food allergy-related anxiety (FAA) contributes to poorer...


Conclusion: Anxiety severity scores on the Scale of Food Allergy Anxiety and the Scale of Child Anxiety–Related Emotional Disorders significantly declined per both child and parent reports.