Ultra-high frequency ultrasound detection of the dermo-epidermal junction: Its potential role in dermatology - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36017602/
Traditional high-frequency ultrasound (HFUS; 20 MHz) is a non-invasive method used to study skin in vivo but is not able to measure skin thickness accurately and to identify the dermal-epidermal...
Conclusion: Ultra-high frequency ultrasound is a useful technique in the field of dermatology which can provide critical information to complement clinical data.
Impact of a decade of research into atopic dermatitis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36162801/
The last decade has seen an unprecedented pace of change, particularly of clinical research in atopic dermatitis (AD). This review summarizes some key discoveries. Over the last 10 years, nearly...
Discussion: The aim of this Clinical Commentary within the tenth Anniversary theme issue of the Journal 47 is to review the most clinically relevant advances in atopic dermatitis (AD) over the last decade.
Food allergy testing in atopic dermatitis
Source : https://www.jaadinternational.org/article/S2666-3287(22)00103-1/fulltext
Food allergy and food-related worsening of dermatitis can occur in patients with atopic dermatitis (AD). We reviewed the relationship of AD with food allergen hypersensitivity and the risks and benefits...
Conclusion: Some younger children with moderate-to-severe AD who failed standard therapy may have FA coexpression or food-triggered AD. Egg, milk, and peanut account for >80% of FA in AD.
Managing Atopic Dermatitis in Skin of Color
Source : https://www.dermatologytimes.com/view/managing-atopic-dermatitis-in-skin-of-color
Despite the recent significant advances in both topical and oral dermatologic therapy, atopic dermatitis (AD) remains a difficult-to-treat skin disease and can be particularly challenging in patients with skin of...
Discussion: All dermatologists should strive to incorporate EASI, BSA, IGA, Patient-Oriented Eczema Measures, and Dermatology Life Quality Index [scores] in their clinical assessments, because what we do in research can easily translate to clinical practice."
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Jeremy Moss, Medical director and physician3yrI agree with Dr Honig that one of the key features of AD that is vexing for skin of color patients is dyspigmentation, both hypo- and hyperpigmentation. It will Show More
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Barbara Honig3yrMore recent and clinically effective steroid-sparing agents, both topical like opzelura and biologics or oral JAKs, are particularly useful in treating AD in skin of color because there is no Show More
Type 2 Inflammation Contributes to Skin Barrier Dysfunction in Atopic Dermatitis
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428921/
JID Innov. 2022 Sep; 2(5): 100131. Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple interacting systems. In AD, skin inflammation is caused by host-environment interactions...
Conclusion: Targeting type 2 cytokines in AD has a broad range of beneficial effects on the components of the skin barrier, including lipids, proteins, skin pH, corneocyte structure, TJs, sweat glands, and the microbiome, reinforcing the notion that AD is a systemic type 2 inflammatory disease.