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Day 1 Highlights from the 2022 American Academy of Dermatology Annual Meeting

The American Academy of Dermatology’s 2022 annual meeting provided opportunities for attendees to learn about the latest advancements in clinical and cosmetic dermatology, including new and emerging treatments for common skin conditions and new tools that dermatologists can use to better diagnose and follow patients with skin diseases.



Click on the image above to view highlights from our team of analysts.


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Pinus koraiensis needle or cone extracts alleviate atopic dermatitis symptoms by regulating immunity and suppressing inflammation in HaCaT cells and Nc/Nga mice

Pinus koraiensis needle or cone extracts alleviate atopic dermatitis symptoms by regulating immunity and suppressing inflammation in HaCaT cells and Nc/Nga mice

Source : https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.14135

Pinus koraiensis needles (PKN) and cones (PKC) have been shown to protect against inflammation and pathogenic bacteria.


In the histological analysis of the dorsal skin, the administration of both extracts significantly decreased mast cell numbers, immune cell infiltration, gaps between the epidermis and dermis, and abnormal cell and nucleus shapes. In conclusion, both PKCX and PKNX treatment alleviated the DNCB-induced clinical symptoms of AD by alleviating...

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Effects of a moisturizer containing pseudo‐ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double‐blind, randomized, controlled left‐right comparison clinical trial

Effects of a moisturizer containing pseudo‐ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double‐blind, randomized, controlled left‐right comparison clinical trial

Source : https://doi.org/10.1111/jocd.14923

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between...


Conclusion: Based on these results, the moisturizer containing pseudo-ceramide and a eucalyptus extract helps recover the sweat function of AD patients.


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Determinants and Effectiveness of BNT162b2 mRNA Vaccination Among Patients with Atopic Dermatitis: A Population-Based Study - American Journal of Clinical Dermatology

Determinants and Effectiveness of BNT162b2 mRNA Vaccination Among Patients with Atopic Dermatitis: A Population-Based Study - American Journal of Clinical Dermatology

Source : https://link.springer.com/article/10.1007/s40257-022-00672-5

Background The effectiveness of messenger RNA coronavirus disease 2019 (COVID-19) vaccines in patients with atopic dermatitis (AD) is yet to be delineated. It remains largely unknown how AD-related immunosuppressive medications...



Key Points:
• Among patients with atopic dermatitis, messenger RNA coronavirus disease 2019 vaccination proved to be highly effective in protecting against coronavirus disease 2019 and its complications.
• There is no indication that immunosuppressive drugs necessitate alternate vaccination strategies in patients with atopic dermatitis.
•...

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Blood transcriptome profiling identifies 2 candidate endotypes of atopic dermatitis

Source : https://doi.org/10.1016/j.jaci.2022.02.001


Conclusion: AD can be stratified into eosinophilic and noneosinophilic endotypes; such stratification may be useful when assessing stratified trial designs and treatment strategies.