micro-community-banner
 
  • Saved

3yr

Signaling sphingolipids are biomarkers for atopic dermatitis prone to disseminated viral infections

Source : https://doi.org/10.1016/j.jaci.2022.02.027


Conclusion Our data point to long-term abnormalities in the S1P signaling system as a biomarker for previous disseminated viral diseases and a potential treatment target in recurring infections.


  • Saved

3yr

Probiotics in the gut-skin axis – the case of kefir

Source : https://www.alies.pt/en/archive/bbr-vol-18-2-2021/10-19277-bbr-18-2-261-en.html

Introduction The adult human intestine includes a complex ecosystem of microorganisms referred to as gut microbiota (1). The intestinal microbiota is linked to important functions in the host, including digestion...



The nutritional and microbiological value of kefir makes its application as a probiotic in the gut-skin relationship a topic of of significant interest.

  • Saved

3yr

RedirectInhibitory effect of α-cubebenoate on atopic dermatitis-like symptoms by regulating Th2/Th1/Th17 balance in vivoing

Source : https://doi.org/10.1016/j.jep.2022.115162


Conclusion: α-Cubebenoate regulates dermal immune responses by suppressing the Th2/Th17/Th1 immune balances, resulting in amelioration of AD-like symptoms and suppression of immune response in lymph nodes. Thereby, this study provides evidence for its therapeutic efficacy in the treatment of AD symptoms.


  • Saved

3yr
Adipose-derived stem cells ameliorate atopic dermatitis by suppressing the IL-17 expression of Th17 cells in an ovalbumin-induced mouse model - Stem Cell Research & Therapy

Adipose-derived stem cells ameliorate atopic dermatitis by suppressing the IL-17 expression of Th17 cells in an ovalbumin-induced mouse model - Stem Cell Research & Therapy

Source : https://stemcellres.biomedcentral.com/articles/10.1186/s13287-022-02774-7

Background Mesenchymal stem cells (MSCs) have therapeutic potential for atopic dermatitis (AD) owing to their immunoregulatory effects. However, the underlying mechanisms associated with the therapeutic efficacy of MSCs on AD...


Conclusion: ADSCs ameliorate OVA-induced AD in mice mainly by downregulating IL-17 secretion of Th17 cells.

  • Saved

3yr
Preview of the 2022 American Academy of Dermatology (AAD) Annual Meeting

The American Academy of Dermatology (AAD) Annual Meeting is being held in Boston this year and runs from March 25 to 29, 2022. AAD members include more than 20,500 physicians worldwide, and the organization is committed to advancing the diagnosis and treatment of the skin, hair, and nails; advocating for high standards in clinical practice, education, and research in dermatology; and supporting and improving patient care.



Click on the image above to view a preview from our team of analysts.