Conclusions: These results highlight severe infant LRTI as an important risk factor for allergic and atopic disease (ie, polysensitization and atopic dermatitis), and they suggest that this risk is independent of maternal in utero environment, both-parent history of asthma, and both-parent genetic predisposition.
A Combined Analysis of Gut and Skin Microbiota in Infants with Food Allergy and Atopic Dermatitis: A Pilot Study
Source : https://doi.org/10.3390/nu13051682
The gut microbiota in patients with food allergy, and the skin microbiota in atopic dermatitis patients differ from those of healthy people. We hypothesize that relationships may exist between gut...
Certain clinical conditions were associated with characteristic bacterial taxa in the skin and gut microbiota. Positive correlations were found between skin and fecal samples in the abundance of Gemella among allergic infants, and Lactobacillus and Bacteroides among healthy infants. Although infants with allergies and healthy infants demonstrate...
Prevalence and characteristics of atopic dermatitis among young adult females and males-report from the Swedish population‐based study BAMSE
Source : https://onlinelibrary.wiley.com/doi/full/10.1111/jdv.17929
E. Melén , N. Ballardini , Corresponding Author N. Ballardini Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden Department...
Conclusions: Atopic dermatitis is a common disease among young adults, and even though more females than males have AD at 24 years, adult onset of AD seems to be equally prevalent among both sexes in young adulthood.
Highlights:
•Novel nanoporous multilayer stack-based sensing platform that works with passive eccrine sweat.
•FLOCK detects cortisol and Interleukin-31 in swear through wearable form-factor.
•Human subject-based testing highlights ability to perform detection in real time and on-body
•Correlation with salivary levels and gold standard...
EXTRACELLULAR MATRIX REMODELING IN ATOPIC DERMATITIS HARNESSES THE ONSET OF AN ASTHMATIC PHENOTYPE AND IS A POTENTIAL CONTRIBUTOR TO THE ATOPIC MARCH
Source : https://www.medrxiv.org/content/10.1101/2022.01.17.22269397v1
The development of atopic dermatitis (AD) in infancy, and subsequent allergic rhinitis, food allergies, and asthma in later childhood, is known as the atopic march. The mechanism is largely unknown,...
One Sentence Summary Atopic skin harbors the progression of atopic diseases to lung tissue through a skin-lung axis that contributes to the atopic march via extracellular matrix remodeling.