Conclusions: Explaining the genetic basis of AD to patients and families may improve compliance with moisturizers and topical anti-inflammatory medications based on their understanding that AD patients are inherently predisposed to skin barrier defects and cutaneous inflammation. Meanwhile, minimizing environmental triggers may lead to...

Conclusions: The results of this study highlight the current unmet medical needs in AD management. This is especially so for adult patients experiencing barriers to JAK inhibitors and biologics with moderate/severe AD whose priority goals of itch relief and skin improvement were not met with topical therapy. There is a need to consider...

Conclusions: Two online interventions for self-management of eczema aimed at parents or carers of children with eczema and at young people with eczema provide a useful, sustained benefit in managing eczema severity in children and young people when offered in addition to usual eczema care.

Conclusions: We present novel findings demonstrating increased neurotrophic and extracellular matrix remodeling signatures in PN compared to AD, possibly explaining the morphological differences in their lesions. These signatures may therefore be important components of the PN pathogenesis and may serve as therapeutic targets.

Conclusions: These biomarkers are potential life quality impairment prediction factors in PSO and AD, this could be very relevant. A challenge in future will be the development of a mechanism to get an adequate amount of sweat, as perspiration may vary from individual to individual. Additionally, the concentration of the biomarkers may vary in...